Reversible Inhibition

Now consider the effect of reversibly-binding inhibitors on an enzyme. If an inhibitor binds
reversibly at the same site as the substrate, the inhibition is referred to as competitive.
If the inhibitor binds to another site on the enzyme, the binding is described as
noncompetitive. These two alternative behaviors may be distinguished by their effects
on Lineweaver-Burk or Hanes-Woolf plots.

Click here to consider competitive inhibition.
Click here to consider noncompetitive inhibition.

References:
Garrett and Grisham, pages 369 - 374.
Lehninger, Nelson, and Cox, pages 220 - 222.
Voet and Voet, pages 340 - 344.